Molecular profiles of high‐grade and low‐grade pseudomyxoma peritonei

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Molecular profiles of high‐grade and low‐grade pseudomyxoma peritonei

Pseudomyxoma peritonei (PMP) is a rare disease exhibiting a distinct clinical feature caused by cancerous cells that produce mucinous fluid in the abdominal cavity. PMPs originate most frequently from the appendix and less frequently from the ovary. This disease can range from benign to malignant, and histologically, PMP is classified into two types: disseminated peritoneal adenomucinosis (DPAM...

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Pseudomyxoma peritonei.

Pseudomyxoma peritonei is a rare, slowly progressive disease that produces extensive mucus accumulation within the abdomen and pelvis. It is managed by cytoreductive surgery involving hyperthermic intraoperative intraperitoneal chemotherapy.

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Pseudomyxoma peritonei.

Pseudomyxoma peritonei is a relatively rare and poorly understood condition in which mucus accumulates within the peritoneal cavity. The presence of cells in the mucin, either inflammatory or neoplastic, distinguishes it from simple acellular mucus ascites caused by mucinous spillage. There is widespread seeding of the peritoneal and omental surfaces with a heavy cancerous glaze. This is princi...

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Pseudomyxoma peritonei.

THE PATIENT WAS a 71-year-old man admitted for the evaluation of an asymptomatic 7-cm thoracic aortic aneurysm. On physical examination, he was noted to have abdominal ascites. A computed tomography scan of the abdomen showed intra-abdominal heterogeneous mucinous material with scalloping of the liver, spleen, and mesentery. The patient underwent a diagnostic laparoscopy that revealed a large a...

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Management of pseudomyxoma peritonei.

Pseudomyxoma peritonei (PMP) is an uncommon clinical condition that typically originates from a perforated epithelial neoplasm of the appendix. The clinical presentation is variable, often with non-specific symptoms and is associated with abdominal distension in advanced cases. Whilst traditionally considered benign, it is apparent that PMP represents a spectrum of disease and, at best, should ...

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ژورنال

عنوان ژورنال: Cancer Medicine

سال: 2015

ISSN: 2045-7634,2045-7634

DOI: 10.1002/cam4.542